Publications and Presentations

Collaborative Research Agreement with Binghamton University
Pharmacy residents and preceptors can take advantage of the 2024 Collaborative Research Agreement (CRA) between Binghamton University and The Guthrie Clinic that paves the way for research initiatives. This agreement has the goal of benefitting outcomes and wellness of the local communities.

Resident

• Assessing reliability of current delirium scoring in the ICU Kaytlin Kelly, Pharm.D., Karen Williams, Pharm.D., Josh Campbell, Pharm.D.
   
  • May 12, 2025 Platform presentation at University of North Carolina Research in Education and Practice Symposium, virtual/Chapel Hill, NC.
     
• Enhancing Timely Access to Medication Changes: The Role of Ambulatory Care Pharmacists in Overcoming Transitions of Care Challenges Alison Van Dyke, Pharm.D., Karen Williams, Pharm.D., Jessica Carswell, Pharm.D., Keith Hughes, Pharm.D.
   
  • May 12, 2025 Platform presentation at University of North Carolina Research in Education and Practice Symposium, virtual/Chapel Hill, NC.
     
  • April 25, 2025 Poster presentation at Guthrie Research Day, Sayre, PA. (04-25 Research Pharm Van Dyke poster) Third prize, Research poster category
     
  • December 11, 2024 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting, New Orleans, LA.
     
• Implementation of Blood Culture Stewardship During a Blood Culture Bottle Shortage: A Multicenter Assessment Kristen Sevilla, Pharm.D., Orest Konyk,MD, Jon C. Rittenberger MD, Karen Williams, Pharm.D.
   
  • May 12, 2025 Platform presentation at University of North Carolina Research in Education and Practice Symposium, virtual/Chapel Hill, NC.
     
  • April 25, 2025 Poster presentation at Guthrie Research Day, Sayre, PA. (04-25 Research Pharm Sevilla poster)
     
  • December 11, 2024 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting, New Orleans, LA.
     
• Inpatient Hypoglycemia and Hyperglycemia Medication Use Evaluation Kristen Sevilla, Pharm.D., Ewa Sulicz, Pharm.D. Candidate, Karen Williams, Pharm.D.
   
  • April 25, 2025 Poster presentation at Guthrie Research Day, Sayre, PA. (04-25 QI Pharm Sevilla poster)
     
• Intraperitoneal Antibiotic usage in relation to the Updated 2022 ISPD Peritonitis Guidelines Kaytlin Kelly, Pharm.D., Nataliia Wojciaczyk, Pharm.D., Karen Williams, Pharm.D.
   
  • April 25, 2025 Poster presentation at Guthrie Research Day, Sayre, PA. (04-25 QI Pharm Kelly poster)
     
• Methadone Administration: A Medication use Evaluation Alison Van Dyke, Pharm.D., Karen Williams, Pharm.D., Jordan Magruder, MD, Keith Hughes, Pharm.D.
   
  • April 25, 2025 Poster presentation at Guthrie Research Day, Sayre, PA. (04-25 QI Pharm Van Dyke poster)
     
• Pharmacist-Led Intervention for Improving Medication Adherence in a Rural Population of Patients with COPD (04_16 Research Pharm Hughes COPD med adherence.pptx) 
  Keith Hughes, Pharm.D.; Karen S Williams, B.S. Pharm, BCPS AQ-ID; Joshua Campbell, Pharm.D., BCCCP ; Jessica Carswell Pharm.D.

  • April 2024 Poster presentation at Guthrie Research Day, Sayre, PA

  • December 2023 Poster presentation at ASHP Midyear Clinical meeting, Anaheim, CA.

  • 2024 ASHP Pharmacy Resident Research Grant Recipient

• Evaluation of Medication Regimen Complexity-ICU (MRC-ICU) Score Before and After Implementation of a Virtual Intensive Care Model in a Multisite, Rural Health-System (04_16 Research Pharm Mastro MRC ICU.pptx)
  David Mastro, Pharm.D.; Karen S Williams, B.S. Pharm, BCPS AQ-ID; Joshua Campbell, Pharm.D., BCCCP

  • April 2024 Poster presentation at Guthrie Research Day, Sayre, PA

  • Mastro D, Williams K, Campbell J. Evaluation of Change in Medication Regimen Complexity-ICU (MRC-ICU) Score Following Implementation of a Virtual Intensive Care Model in a Multisite, Rural Health-System. J Pharm Pract. Published online September 6, 2025. doi:10.1177/08971900251370888

  • December 2023 Poster presentation at ASHP Midyear Clinical meeting, Anaheim, CA.

• Impact of Medication Optimization by Pharmacists in a Rural Population of Patient with Acute COPD Exacerbations (04_16 Research Pharm Noldy_Med Opt by Rx in AECOPD.pptx)
  Andrea Noldy, Pharm.D.; Jessica Carswell Pharm.D.; Karen S Williams, B.S. Pharm, BCPS AQ-ID

  • April 2024 Poster presentation at Guthrie Research Day, Sayre, PA

• The efficacy of steroid sparing anti-emetic therapy in patients treated with high or moderate emetogenic chemotherapy (please create a new file for this: Research Pharm Ink Day Poster Final.pptx)
  Nicole Ink, Pharm.D., Kelly Wurzler, Pharm.D., Zane Waite, Pharm.D., BCOP
  • December 2022 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting, Las Vegas, NV.
  • April 2023 Oral & Poster presentation at Guthrie Research Day, Sayre, PA 
  • Third Prize, Oral Presentations
     
• Evaluation of blood culture contamination rates and costs after implementation of initial specimen diversion device in a rural emergency department with staff turnover (please provide a new link to Research Pharm Hanrahan ASHP Guthrie Research Day Poster.pptx)
  Kathleen Hanrahan, PharmD, Karen S Williams, PharmD, BCPS-AQ-ID; Joshua Campbell, PharmD, BCCCP
  • December 2022 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting, Las Vegas, NV.
  • April 2023 Oral & Poster presentation at Guthrie Research Day, Sayre, PA 
     
• Evaluation of a revised anesthesia recovery order set on opioid use and pain scores in the post-anesthesia care setting at a rural health system (please provide a new link to Research Pharm Kam.pdf)
  Brian Kam, PharmD, Karen S Williams, PharmD, BCPS-AQ-ID; Sri Senapathi, MD, Burdett Porter, MD, Kimberly Joedicke, Pharm.D., CPPS
  • December 2022 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting, Las Vegas, NV
  • April 2023 Poster presentation at Guthrie Research Day, Sayre, PA 
  • Kam B, Williams K, Senapathi S, Burdett Porter ;, Joedicke K. Evaluation of a Revised Anesthesia Recovery Order Set on Opioid Use and Pain Scores in the Postanesthesia Care Setting at a Rural Health System. https://doi.org/103138/guthrie-2023-0006. Published online August 13, 2025. doi:10.3138/GUTHRIE-2023-0006
     
• Assessing knowledge and attitudes of nursing staff regarding congestive heart failure medication regimens and impact on patient understanding post-discharge
  Alena Thannikal, PharmD, Karen S Williams, PharmD, BCPS-AQ-ID; Joshua Campbell, PharmD, BCCCP; Lucy Stephens, PharmD, BCPS
  • December 2021 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting (virtual)
  • April 2022 Poster presentation at Guthrie Research Day, Sayre, PA 
  • Thannikal A, Campbell J, Ellis L, Williams KS. The Guthrie Journal. 2023;75(1):17-25.
     
• Improving Harm Reduction Services in People Who Inject Drugs at a Rural Health System
  Amandeep Kaur, PharmD; Karen S. Williams, PharmD, BCPS-AQ ID; Laura J. Walker, DO
  • December 2021 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting (virtual)
  • April 2022 Oral & Poster presentation at Guthrie Research Day, Sayre, PA 
  • Kaur A, Williams KS. The Guthrie Journal 2023;75(1):39-44.
     
• Improving time to appropriate antibiotics in septic patients using interdisciplinary care and artificial intelligence. 
  Brittany Fuller, Pharm.D., Melanie Fazzolari, Pharm.D., Karen Williams, Pharm.D., BCPS AQ-ID, Lea Scopelliti, Lucy Stephens, Pharm.D., BCPS
  • December 2020 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting (virtual)
  • April 2021 Oral & Poster presentation at Guthrie Research Day, Sayre, PA 
     
• Comparing identification of adverse effects from immune checkpoint inhibitors between a traditional adverse effect tool and a modified immune-related adverse effect tool
  Alec J. Romanowski, Pharm.D., Zane M. Waite, Pharm.D., BCOP
  • December 2020 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting, (virtual)
  • April 2021 Oral & Poster presentation at Guthrie Research Day, (virtual)
     
• Impact of an interdisciplinary team on time to administration of appropriate initial antibiotics in suspected septic patients presenting to the emergency department
  Melanie Fazzolari, Pharm.D, Zachary Dewar, MD, Karen Williams, Pharm.D., BCPS AQ-ID
  • April 2020 Oral & Poster presentation at Guthrie Research Day (virtual)
  • First place presentation in Interdisciplinary team category
     
• Evaluation of pharmacist led inhaler technique education in patients with chronic obstructive pulmonary disease  
  Kristeen Alazruei, Pharm.D., Josh Campbell, Pharm.D., BCCCP
  • April 2020 Oral & Poster presentation at Guthrie Research Day (virtual)
     
• Why am I back? Patients’ perspective on 30-day hospital readmission 
  Khalid Srour, Pharm.D., Joshua Campbell, Pharm.D., BCCCP
  • December 2018 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting, Anaheim, CA
  • April 2019 Oral & Poster presentation at Guthrie Research Day, Sayre, PA 
     
• Moon JS, Srour KJ, Williams KS. QI: Does Guthrie “C.diff”erences in treatment of Clostridioides difficile? Poster session presented at Stanley Conklin Research Day; 2019 April 5; Sayre, PA. 
   
• Evaluation of empiric meropenem utilization in a community teaching hospital (Please create a new file for this: Meropenem Poster.pptx)
  Authors:  Jibi Philip, Pharm.D., Karen Williams, Pharm.D., BCPS
  • December 2017 Poster presentation at American Society of Health-System Pharmacists (ASHP) Midyear Clinical meeting, Orlando, FL

Preceptor

• Spellberg B, Wald-Dickler N, Holtom P, ...Williams KS, Wojciaczyk N, et al. Static vs. cidal: it’s not complex; it’s simply incorrect. Uhlemann AC, ed. Antimicrob Agents Chemother. Published online July 21, 2025. doi:10.1128/AAC.00513-25
   
• Mastro D, Kujawski S. What Every Pharmacist Should Know about Enteral Nutrition and Medications. October 21, 2024: tl;dr Pharmacy. Available at https://www.tldrpharmacy.com/content/what-every-pharmacist-should-know-about-enteral-nutrition-and-medications
   
• Mastro D, Kujawski S. The pharmacist’s quick(ish) primer on status epilepticus. March 26, 2024. : tl;dr Pharmacy. Available at https://www.tldrpharmacy.com/content/the-pharmacists-quickish-primer-on-status-epilepticus
   
• Pachpande V, Senapathi SHV, Williams K, Chai S, Mandal S, Prabhu S. Demographics, comorbidities, and laboratory parameters in hospitalized patients with SARS-CoV2 infection at a community hospital in rural Pennsylvania. PLoS One. 2022 Apr 27;17(4):e0267468. doi: 10.1371/journal.pone.0267468. PMID: 35476841; PMCID: PMC9045616.
   
• Khadka S, Williams K, Solanki S. Remdesivir-Associated Pancreatitis. Am J Ther. 2022 Jul 1;29(4):e444-e446. doi: 10.1097/MJT.0000000000001266.PMID: 33590992
   
• Sikora A, Ayyala D, Rech M, Blackwell S, Campbell J, Caylor M, Condeni Smith M, DePriest A, Dzierba A, Flannery A, Hamilton L, Heavner M, Horng M, Lam J, Liang E, Montero J, Murphy D, Plewa-Rusiecki A, Sacco A, Sacha G, Shah P, Smith M, Smith Z, Radosevich J, Vilella A, MRC-ICU Investigator Team. Impact of Pharmacists to Improve Patient Care in the Critically Ill: A Large Multicenter Analysis Using Meaningful Metrics With the Medication Regimen Complexity-ICU (MRC-ICU) Score. Critical Care Medicine. 2022 Sept 1; 50 (9): 1318-1328
   
• Brown J, Guru S, Williams K, Florentino R, Miner J, Cagir B. Rural Healthcare Center Preparation and Readiness Response to Threat of COVID-19 Journal of the American College of Surgeons 2020;230(6):1105-10. DOI: 10.1016/J.JAMCOLLSURG.2020.04.006
   
• Jorgensen SCJ, Murray KP, Lagnf AM, Melvin S, Bhatia S, Shamim MD, Smith JR, Brade KD, Simon SP, Nagel J, Williams KS, Ortwine JK, Veve MP, Truong J, Huang DB, Davis SL, Rybak MJ. A Multicenter Evaluation of Vancomycin-Associated Acute Kidney Injury in Hospitalized Patients with Acute Bacterial Skin and Skin Structure Infections. Infectious Diseases and Therapy 2020 9:89-06. DOI: 10.1007/S40121-019-00278-1 0
   
• Impact of a therapeutic interchange program on discharge medication reconciliation (Please create a new file for this: ASHP Poster - Impact of a Therapeutic Interchange Program on Discharge Medication Reconciliation.ppt)
  Presenter(s): Kimberly Joedicke, Pharm.D.
  • December 2019 Poster presentation at ASHP Midyear Clinical Meeting, Las Vegas, NV
     
• Provider Knowledge and Attitudes Towards Antibiotic Prescribing and Antibiotic Stewardship in Outpatient Rural Clinics
  Presenter(s): Wesley D. Kufel, PharmD, BCPS, AAHIVP, Bryan T. Mogle, PharmD, BCPS, AAHIVP, Karen S. Williams, PharmD, BCPS-AQ ID, Keri A. Mastro, PharmD Candidate, James Jester, PharmD, John Snyder, PharmD, BCPS, Theresa J. Lubowski, PharmD, KarenBeth H. Bohan, PharmD, BCPS
  • October 2018 Poster presentation at IDWeek, San Francisco, CA
  • Kufel WD, et al. Journal of the American College of Clinical Pharmacy (JACCP): December 2019.  doi: 10.1002/jac5.1198
     
• Bennett Doughty, L. Nathan Tumey, and Karen Williams (2019) Case report: Albendazole associated psychosis. Mental Health Clinician: November 2019, Vol. 9, No. 6, pp. 397-400
   
• Impact of Antimicrobial Stewardship Commitment Posters on Antibiotic Prescribing for Upper Respiratory Tract Infections in a Rural Outpatient Setting
  Presenter(s): Wesley D. Kufel, PharmD, BCPS, AAHIVP, Wesley D. Kufel, PharmD, BCPS, AAHIVP, Karen Williams, PharmD, BCPS-AQ ID, Caitlin Cushna, Utkarsh Dang, PhD, KarenBeth H. Bohan, PharmD, BCPS
  • October 2018 Poster presentation at IDWeek, San Francisco, CA
     
• Improving time to first dose of broad spectrum antibiotics in patients with severe sepsis utilizing a Pharmacy Antibiotic Alert. (please add link for file Pharmacy Antibiotic Alert Poster (Stephens, L, Williams K - Guthrie Robert Packer Hospital).pdf)
  Authors: Lucy Stephens, Pharm.D., Karen Williams, Pharm.D., BCPS
  • December 2017 Poster presentation at ASHP Midyear Clinical Meeting, Orlando, FL

Other resident QI/Patient Safety projects/Medication Use Evaluations have included:

• Assessment of management of asymptomatic bacteriuria
• Evaluation of andexanet alfa utilization
• Evaluation of management of hypercalcemia
• Evaluation of management of C. difficile​​​​​
• Evaluation of methylnaltrexone utilization
• Evaluation of hyper and hypoglycemia
• Evaluation of methadone prescribing
• Evaluation of treatment of peritonitis