Current Clinical Trials

Department: Gastroenterology
Diagnosis: Gastrointestinal - Ulcerative Colitis
Principal Investigator: Georgetson MD, FACG, Michael
Sponsor: AbbVie
Details (Identifier #): NCT03006068
Title: M14-533, A Phase 3 Multicenter, Open-Label Extension (OLE) Study to Evaluate the Long-Term Safety and Efficacy of ABT-494 in Subjects with Ulcerative Colitis (UC)
Department: Cardiology
Diagnosis: Cardiac - Arrhythmia
Principal Investigator: Deshmukh MD, Pramod
Sponsor: Internal FDN
Details (Identifier #): NCT02931253
Title: Metformin as an Upstream Therapy in Atrial Fibrillation
Department: Gastroenterology
Diagnosis: Gastrointestinal - Crohn's
Principal Investigator: McDonald M.D., Thomas
Sponsor: Eli Lilly
Details (Identifier #): NCT02891226
Title: 16T-MC-AMAG, A Phase 2, Multicenter, Randomized, Parallel-Arm, Placebo-Controlled Study of LY3074828 in Subjects With Active Crohn's Disease (SERENITY)
Department: Oncology
Diagnosis: Gastrointestinal - Liver
Principal Investigator: Banerjee MD, Sima
Sponsor: Internal
Details (Identifier #): none
Title: A Humanitarian Device Exemption Use Protocol of TheraSphere For Treatment of Unresectable Primary or Secondary Liver Neoplasia
Department: Surgery
Diagnosis: Gastrointestinal - Miscellaneous
Principal Investigator: Sadik MD, Karim
Sponsor: Internal FDN
Details (Identifier #): NCT02250924
Title: Prospective, Randomized caffeinated Gum to Prevent Post-Operative Ileus: A , Placebo-controlled trial
Department: Gastroenterology
Diagnosis: Gastrointestinal - Miscellaneous
Principal Investigator: Georgetson MD, FACG, Michael
Sponsor: Seres
Details (Identifier #): NCT03183128
Title: A Phase 3 Multicenter, RandomizeEd, Double Blind, Placebo COntrolled, Parallel Group Study to Evaluate the Safety, Tolerability, & Efficacy of SER-109 vs. Placebo to Reduce Recurrence of ClOstRidium Difficile Infection (CDI) in Adults (SERES-012)
Department: Cardiology
Diagnosis: Cardiac - Arrhythmia
Principal Investigator: Deshmukh MD, Pramod
Sponsor: Abbott
Details (Identifier #): NCT03170583
Title: SJM Brady MRI Post Approval Study
Department: Cardiology
Diagnosis: Cardiac - Miscellaneous
Principal Investigator: Sporn M.D., Daniel
Sponsor: Internal FDN
Details (Identifier #): NCT02373527
Title: Strict Versus No Fasting Prior to Cardiac Catheterization: A Prospective Evaluation of Safety and Clinical Outcomes
Department: Gastroenterology
Diagnosis: Gastrointestinal - Miscellaneous
Principal Investigator: Georgetson MD, FACG, Michael
Sponsor: Seres
Details (Identifier #): NCT03183141
Title: ECOSPOR IV: AN OPEN-LABEL EXTENSION OF STUDY SERES-012 EVALUATING SER-109 IN ADULT SUBJECTS WITH RECURRENT CLOSTRIDIUM DIFFICILE INFECTION (RCDI)
Department: Oncology
Diagnosis: Head and Neck
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: BMS
Details (Identifier #): NCT02823574
Title: BMS CA209-714,A Double-Blind, Randomized, Two Arm Phase 2 Study of Nivolumab in Combination with Ipilimumab versus Nivolumab in combination with Ipilimumab placebo Squamous Cell Carcinoma of the Head and Neck (SCCHN) (CheckMate 714: CHECKpoint pathway and nivoluMAb clinical Trial Evaluation 714)
Department: Cardiology
Diagnosis: Cardiac - Surgery
Principal Investigator: Sporn M.D., Daniel
Sponsor: Abbott VD
Details (Identifier #): n/a
Title: GRAFTMASTER® RX Coronary Stent Graft System(JOSTENT)
Department: Gastroenterology
Diagnosis: Gastrointestinal - Liver
Principal Investigator: McDonald M.D., Thomas
Sponsor: Gilead Sciences
Details (Identifier #): NCT03053050
Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis
Department: Oncology
Diagnosis: Lung- Non-Small Cell
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: BMS
Details (Identifier #): NCT02869789
Title: BMS CA209-817, A Phase IIIb/IV Safety and Efficacy Trial of Flat Dose Nivolumab in Combination with Ipilimumab in Participants with Non-Small Cell Lung Cancer
Department: Gastroenterology
Diagnosis: Gastrointestinal - Ulcerative Colitis
Principal Investigator: Srivatana M.D., Ukorn
Sponsor: AbbVie
Details (Identifier #): NCT01848561
Title: Legacy P11-282, A Long-Term Non-Interventional Registry to Assess Safety and Effectiveness of HUMIRA® (Adalimumab) in Patients with Moderately to Severely Active Ulcerative Colitis (UC)
Department: Gastroenterology
Diagnosis: Gastrointestinal - Liver
Principal Investigator: McDonald M.D., Thomas
Sponsor: Gilead Sciences
Details (Identifier #): NCT03053063
Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis (NASH)
Department: Pulmonary
Diagnosis: Lung - COPD
Principal Investigator: Walsh MD, James
Sponsor: GSK
Title: Post-authorisation Safety (PAS) Observational Cohort Study to Quantify the Incidence and Comparative Safety of Selected Cardiovascular and Cerebrovascular Events in COPD Patients Using Inhaled UMEC/VI Combination or Inhaled UMEC versus Tiotropium (Study 201038)
Department: Cardiology
Diagnosis: Cardiac - Congestive Heart Failure
Principal Investigator: Sattur MD, Sudhakar
Sub-Investigator(s):
Sponsor: Astra Zeneca
Details (Identifier #): NCT02917031
Title: AstraZeneca D1680C00016, MEASURE-HF, MEchAniStic evalUation of glucose-loweRing strategiEs in patients with Heart Failure; A 24-Week, Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Study to Investigate the Effects of Saxagliptin and Sitagliptin in Patients with Type 2 Diabetes Mellitus and Heart Failure
Department: Gastroenterology
Diagnosis: Gastrointestinal - Ulcerative Colitis
Principal Investigator: Georgetson MD, FACG, Michael
Sponsor: Janssen
Details (Identifier #): NCT02407236
Title: CNTO1275UCO3001, A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Protocol to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
Department: Gastroenterology
Diagnosis: Gastrointestinal - Miscellaneous
Principal Investigator: McDonald M.D., Thomas
Sponsor: Janssen
Details (Identifier #): none
Title: Limited access protocol for the use of oral cisapride in the treatment of refractory gastroesophageal reflux disease and other gastrointestinal motility disorders. CIS-USA-154
Department: Oncology
Diagnosis: Breast- Metastatic
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: MacroGenics
Details (Identifier #): NCT02492711
Title: MacroGenics SOPHIA, CP-MGAH22-04, A Phase 3, Randomized Study of Margetuximab Plus Chemotherapy vs. Trastuzumab Plus Chemotherapy in the Treatment of Patients with HER2+ Metastatic Breast Cancer Who Have Received Prior Anti-HER2 Therapies and Require Systemic Treatment
Department: Oncology
Diagnosis: Breast
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ECOG
Details (Identifier #): NCT02115282
Title: E2112, A Randomized Phase III Trial of Endocrine Therapy Plus Entinostat/Placebo in Patients With Hormone Receptor-Positive Advanced Breast Cancer
Department: Oncology
Diagnosis: Lung- Non-Small Cell
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: Mirati
Details (Identifier #): NCT02544633
Title: Mirati 265-109 Amethyst, A Phase 2, Parallel-Arm Study of MGCD265 in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer with Activating Genetic Alterations in Mesenchymal-Epithelial Transition Factor
Department: Oncology
Diagnosis: Oncology - General
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ECOG
Details (Identifier #): NCT02201992
Title: E4512, A Randomized Phase III Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Observation for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein
Department: Oncology
Diagnosis: Oncology - General
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: Mirati
Details (Identifier #): NCT02219711
Title: Mirati 516-001: A Phase 1/1b Study of MGCD516 in Patients With Advanced Solid Tumor Malignancies
Department: Oncology
Diagnosis: Breast
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ALLIANCE
Details (Identifier #): NCT02750826
Title: Alliance A011401, Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer
Department: Oncology
Diagnosis: Breast
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ECOG
Details (Identifier #): NCT02445391
Title: EA1131, A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy vs. Capecitabine in Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy
Department: Oncology
Diagnosis: Genito-urinary - Miscellaneous
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: NCI
Details (Identifier #): NCT02446600
Title: NRG-GY004, A Phase III study comparing single-agent olaparib or the combination of cediranib and olaparib to standard platinum-based chemotherapy in women with recurrent platinum-sensitive ovarian, fallopian tube, or primary peritoneal cancer.
Department: Oncology
Diagnosis: Breast
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ALLIANCE
Details (Identifier #): NCT02927249
Title: A011502, A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive HER2 Negative Breast Cancer: The ABC Trial
Department: Oncology
Diagnosis: Lung- Non-Small Cell
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ECOG
Details (Identifier #): NCT02595944
Title: EA5142, Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)-A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
Department: Oncology
Diagnosis: Gastrointestinal - Pancreas
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: RTOG
Details (Identifier #): NCT01013649
Title: RTOG-0848, A Phase II-R and A Phase III Trial Evaluating Both Erlotinib (Ph II-R) and Chemoradiation (Ph III) as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma
Department: Oncology
Diagnosis: Brain
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ALLIANCE
Details (Identifier #): NCT02152982
Title: Alliance A071102, A Phase II/III Randomized Trial of Veliparib or Placebo in Combination with Adjuvant Temozolomide in Newly Diagnosed Glioblastoma with MGMT Promoter Hypermethylation
Department: Oncology
Diagnosis: Melanoma
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ECOG
Details (Identifier #): NCT02224781
Title: EA6134, A Randomized Phase III trial of Dabrafenib + Trametinib followed by Ipilimumab + Nivolumab at Progression vs. Ipilimumab + Nivolumab followed by Dabrafenib + Trametinib at Progression in Patients With Advanced BRAFV600 Mutant Melanoma
Department: Oncology
Diagnosis: Lung- Miscellaneous
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: SWOG
Details (Identifier #): NCT02154490
Title: S1400, Phase II/III Biomarker-Driven Master Protocol for Second Line Therapy of Squamous Cell Lung Cancer
Department: Oncology
Diagnosis: Lung- Non-Small Cell
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ALLIANCE
Details (Identifier #): NCT02193282
Title: A081105, Randomized Study of Erlotinib or Observation in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)
Department: Cardiology
Diagnosis: Cardiac - Congestive Heart Failure
Principal Investigator: Deshmukh MD, Pramod
Sponsor: Impulse
Details (Identifier #): NCT03102437
Title: FIX-HF-5CA: Continued Access Protocol for the Evaluation of the OPTIMIZER Smart System in Subjects with Moderate-to-Severe Heart Failure with Ejection Fraction between 25% and 45%
Department: Oncology
Diagnosis: Breast- Metastatic
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: SWOG
Details (Identifier #): NCT02595905
Title: S1416, Phase II Randomized Placebo-Controlled Trial of Cisplatin With or Without ABT-888 (Veliparib) in Metastatic Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast Cancer
Department: Oncology
Diagnosis: Lung- Miscellaneous
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: ALLIANCE
Details (Identifier #): NCT02194738
Title: Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
Department: Oncology
Diagnosis: Lung- Small Cell
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: G1Therapeutics
Details (Identifier #): NCT02514447
Title: G1T28-03, Phase 1b/2a Safety and Pharmacokinetic Study of G1T28 in Patients with Previously Treated Extensive-Stage Small Cell Lung Cancer (SCLC) Receiving Topotecan Chemotherapy
Department: Oncology
Diagnosis: Oncology - General
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: SWOG
Details (Identifier #): NCT02562716
Title: S1505, A Randomized Phase II Study of Perioperative mFolfironix Versus Gemcitabine/Nab-paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma
Department: Neurology
Diagnosis: Neurology
Principal Investigator: Jasti MD, Venkata
Sub-Investigator(s):
Sponsor: Duke
Details (Identifier #): NCT02478177
Title: Management of Acute Stroke Patients on Treatment with New Oral Anticoagulants: Addressing Real-world Anticoagulant Management Issues in Stroke (ARAMIS) Registry"
Department: Cardiology
Diagnosis: Cardiac - Congestive Heart Failure
Principal Investigator: Kaluski MD, Edo
Sponsor: Zoll
Details (Identifier #): NCT03016754
Title: Heart Failure Optimization Study (HF Opt)
Department: Oncology
Diagnosis: Lung- Non-Small Cell
Principal Investigator: Lowry MD, Philip
Sub-Investigator(s):
Sponsor: SWOG
Details (Identifier #): NCT02642042
Title: S1507, A Phase II Trial of Trametinib With Docetaxel in Patients With KRAS Mutation Positive Non-small Cell Lung Cancer (NSCLC) and Progressive Disease Following One or Two Prior Systemic Therapies
Department: Gastroenterology
Diagnosis: Gastrointestinal - Ulcerative Colitis
Principal Investigator: Georgetson MD, FACG, Michael
Sponsor: AbbVie
Details (Identifier #): NCT02819635
Title: AbbVie M14-234, A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
Department: Neurology
Diagnosis: Neurology
Principal Investigator: Meyer MD, Michael
Sponsor: ACRIN
Details (Identifier #): NCT02420756
Title: Imaging Dementia—Evidence for Amyloid Scanning (IDEAS) Study: A Coverage with Evidence Development Longitudinal Cohort Study
Department: Cardiology
Diagnosis: Cardiac - Acute Coronary Syndrome
Principal Investigator: Sattur MD, Sudhakar
Sub-Investigator(s):
Sponsor: DCRI
Details (Identifier #): NCT02939976
Title: Study of Access Site for Enhancing PCI in STEMI for Seniors (SAFE PCI in STEMI for Seniors)